Alzheimers disease 2 || mbbs || Genetics and pathophysiology

🧠 Genetics & Pathophysiology of Alzheimer’s Disease | Neurotransmitters in Neuropsychiatric Disorders | Clinical Questions Welcome to Preet Medical School! 🩺 In this video, we explore the genetics and pathophysiology of Alzheimer’s disease, understand the role of different neurotransmitters in various neuropsychiatric and neurological disorders, and practice important clinical questions for NEET PG, INI-CET, and MBBS examinations. 📚 Topics Covered in This Video: 🔹 1. Genetics of Alzheimer’s Disease APP, PSEN1, and PSEN2 mutations APOE ε4 and its association with Alzheimer’s disease Early-onset vs. late-onset Alzheimer’s disease Genetic factors and disease progression 🔹 2. Pathophysiology of Alzheimer’s Disease Amyloid-beta (Aβ) deposition and senile plaques Tau hyperphosphorylation and neurofibrillary tangles Synaptic dysfunction and neuronal degeneration Cholinergic hypothesis and cognitive impairment 🔹 3. Neurotransmitters in Neurological & Neuropsychiatric Disorders Acetylcholine — Alzheimer’s disease Dopamine — Parkinson’s disease and schizophrenia Serotonin — depression and anxiety disorders GABA — anxiety and seizure disorders Glutamate — excitotoxicity and neurodegeneration Norepinephrine — mood, attention, and arousal 🔹 4. Clinical Questions & Exam-Oriented Discussion High-yield clinical vignettes Important concepts for NEET PG and INI-CET Differential diagnosis and elimination of incorrect options Frequently tested concepts and clinical correlations 🎯 Who Should Watch? MBBS students NEET PG aspirants INI-CET aspirants Medical students interested in integrated neurology and psychiatry 📌 Our Goal: To understand concepts, connect basic sciences with clinical medicine, and improve clinical reasoning through exam-oriented questions. If you find this video useful, LIKE, SHARE, and SUBSCRIBE to Preet Medical School for more medical lectures, high-yield clinical questions, and integrated subject discussions. 💬 Comment below: Which topic should we cover next? #AlzheimersDisease #Neurotransmitters #NEETPG #INICET #Neurology #Psychiatry #MedicalEducation #Pathophysiology #MedicalStudents #PreetMedicalSchool