From Loading to Remodeling with Timelapsed HR-pQCT (2026 September Webinar)

Early Career Investigator Monthly Webinar Series - September 2026 Presenter: Dr. Matthias Walle Posdoctoral Research Fellow University of Calgary, Canada How does bone sense and respond to its mechanical environment in vivo? Timelapsed high-resolution peripheral quantitative computed tomography (HR-pQCT) offers a powerful way to move beyond static measures of bone structure by mapping where bone formation and resorption occur over time. When combined with finite element analysis, these remodeling patterns can be related to the local mechanical environment to investigate bone mechanoregulation directly. This webinar will introduce the underlying concepts and showcase applications in diabetes and spaceflight, before moving into a hands-on 3D Slicer demonstration of image registration, remodeling analysis, finite element modeling, and visualization of bone adaptation. Disclaimer: Educational Use Only This audio/video recording is intended solely for educational and instructional purposes. It may contain proprietary information, copyrighted material, or personal contributions from individuals. Unauthorized recording, reproduction, distribution, or use of this content for commercial purposes is strictly prohibited. By accessing or using this recording, you agree to respect the intellectual property rights of the creators and participants. Any opinions expressed are those of the speakers and do not necessarily reflect the views of the organization. For questions regarding appropriate use, please email isbm.society@gmail.com.